Flight
Allegiant airlines is usually the cheapest flight (and it's direct) into Savannah from Indianapolis, Cincinnati, Louisville, La Guardia, Midway, and some others. There are plenty of rental car options. Uber/Lyft is really affordable in the area, $20-30 from airport into town, $10ish around town, $15-20 from town to the beach. If you are staying more than a couple days and planning for activities outside the wedding, a rental car will likely be less expensive and more convenient.