If you have a car you can drive to Lago di Como which is about 1.5 hours from Lago Maggiore.
We recommend organizing a trip with Borroni Events to Zermatt, Switzerland and the Matterhorn. Zermatt is a 2 hour drive from Stresa.
We recommend you fly into Milan (MXP) and spend a few days exploring the city!
Take the ferry from Stresa to Isola Bella, Isola Pescatori, and Isola Madre. A hop-on hop-off boat ticket from Stresa is ~$10.
The Bernina Express is the most picturesque train trip in Europe running between Tirano, Italy & Chur, Switzerland. The Express train winds through the Italian and SwissAlps, through 55 tunnels and over 196 bridges and is a UNESCO World Heritage site. From Chur, Switzerland you catch another train & end up in Zurich, Switzerland. Ride duration is approximately 4 hours.