There's a number of options available to get to Issoire.
Please click on the link below to see the options (driving, by plane, by train)
Hotels in Issoire are limited however if you are driving you could find a BnB or hotel in many of the surrounding villages.
Hotel
The Originals Boutique, Hôtel Le Pariou, Issoire (Qualys-Hotel)
18 Avenue John Fitzgerald Kennedy, Issoire, Auvergne-Rhône-Alpes 63500, France
This is located not far from the town centre, making it ideal for getting to the ceremony. This hotel seems to also cater for English speaking people.
Hotel
ibis Issoire
Rue Jean Bigot, Issoire, Auvergne-Rhône-Alpes 63500, France
A little further out but much more rooms and a cheaper option.